肝豆状核变性属常染色体隐性遗传性疾病,国内多采用锌剂和青霉胺治疗。文献报道及教科书均认为青霉胺剂量为20mg(kg·d),每日分2～3次口服。但由于其副作用明显,多于治疗过程中被迫停药。为此,近2年来,我们采用两种剂量青霉胺予以治疗,并分别观察其排铜曲线及副作用,以便?.. Hepatolenticular degeneration is an autosomal recessive genetic disease, the domestic use of zinc agents and penicillamine treatment. Reported in the literature and textbooks that penicillamine dose of 20mg (kg · d), 2 to 3 times daily oral. However, because of its obvious side effects, more than the treatment was forced to stop the process. To this end, the past two years, we use two doses of penicillamine to be treated, and were observed in the copper row and side effects curve, so?