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目的探讨急性白血病患儿的睡眠紊乱与疲乏的相关性。方法采用便利抽样选取65名急性白血病儿童病例,对其主要照顾者进行问卷调查,内容包括儿童睡眠紊乱量表(Sleep Disturbance Scale for Children,SDSC)和PedsQL TMMFS儿童多维疲乏量表。结果急性白血病患儿的睡眠量表总分为(47.83±10.74)分,睡眠紊乱总发生率为6.15%,各维度中睡眠-觉醒转换障碍和睡眠呼吸障碍和觉醒障碍发生率最高。疲乏总分为(60.41±17.26)分,三个维度得分由低到高依次为一般疲乏、休息疲乏和认知疲乏。患儿的睡眠紊乱与疲乏呈负相关(r=-0.51,P<0.01),即患儿睡眠紊乱越严重,疲乏程度越高。结论急性白血病患儿治疗期间最常见的睡眠紊乱为睡眠-觉醒转换障碍和睡眠呼吸障碍和觉醒障碍,疲乏主要表现为一般疲乏和休息疲乏。急性白血病患儿的睡眠障碍与疲乏状况呈负相关。
Objective To investigate the relationship between sleep disturbance and fatigue in children with acute leukemia. Methods Sixty-five children with acute leukemia were selected by means of convenience sampling. The main caregivers were surveyed by questionnaire, which included Sleep Disturbance Scale for Children (SDSC) and PedsQL TMMFS children’s multidimensional fatigue scale. Results The total score of sleep scale of children with acute leukemia was (47.83 ± 10.74) points and the total incidence of sleep disorders was 6.15%. The incidence of sleep-wake change disorder and sleep-disordered breathing and awakening disorder were the highest in all dimensions. The total score of fatigue was (60.41 ± 17.26) points. The scores of the three dimensions from low to high were general fatigue, rest fatigue and cognitive fatigue. Children with sleep disorders and fatigue was negatively correlated (r = -0.51, P <0.01), that is, the more serious children with sleep disorders, the higher the degree of fatigue. Conclusion The most common sleep disturbances in children with acute leukemia are sleep-wake change disorder and sleep-disordered breathing and awakening disorders. The main symptoms of fatigue are general fatigue and rest fatigue. Children with acute leukemia sleep disorders and fatigue was negatively correlated.