气候性滴状角膜变性合并翼状胬肉流行病学特点

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目的:了解呼伦贝尔地区气候性滴状角膜变性(CDK)合并翼状胬肉的流行病学特点及致病因素相关性。方法:对呼伦贝尔地区牧业四旗进行人群抽样调查,并根据可能致病相关因素进行问卷调查。结果:在呼伦贝尔地区牧业四旗共调查2 558人,其中CDK患者553例;在上述人群中,翼状胬肉发病134例,总体患病率5.2%,男性患病率5.1%,女性患病率5.3%,男女发病无差异,总体患病率随年龄增长而逐渐增高;患有CDK的人群,其翼状胬肉患病率为14.1%,明显高于无CDK人群患病率2.8%,二者比较差异有统计学意义(χ2=111.73,P<0.01);游牧民族翼状胬肉患病率为8.7%,高于非游牧民族患病率4.2%,二者差异有统计学意义(χ2=16.66,P<0.01)。CDK分级的越高,翼状胬肉患病率越高,未患CDK者翼状胬肉患病率为2.8%,1级者9.3%,2级者20.2%;巴尔虎蒙古族患病率最高10.2%,其中患有CDK者(16.3%)明显高于无CDK者(3.4%),布里亚特蒙古族、鄂温克族、科尔沁蒙古族和汉族等患病率较低。结论:呼伦贝尔地区气候性滴状角膜变性合并翼状胬肉患病率明显高于未合并CDK者,游牧民族高于非游牧民族;不同民族患病率不同,其发生及严重程度与放牧时间、年龄、民族及生活方式有关。 Objective: To understand the epidemiological characteristics and risk factors of epidemic drop-shaped corneal degeneration (CDK) with pterygium in Hulunbeier area. Methods: A population sampling survey was carried out on the four flags of animal husbandry in Hulunbeier region and a questionnaire survey was conducted on the basis of factors that may cause disease. Results: A total of 2 558 people were surveyed in Hulun Buir’s Four Areas of Livestock Industry, of which 553 were CDK patients. Among the above-mentioned population, 134 cases of pterygium were found, with an overall prevalence rate of 5.2%, a prevalence rate of 5.1% in males and a prevalence of females Rate of 5.3%, no difference between male and female incidence, the overall prevalence increased with age and gradually increased; CDK population, the prevalence of pterygium was 14.1%, significantly higher than the prevalence of non-CDK population prevalence of 2.8%, two (Χ2 = 111.73, P <0.01). The prevalence rate of nomadic pterygium was 8.7%, which was higher than that of non-nomads (4.2%), the difference was statistically significant (χ2 = 16.66, P <0.01). The higher the grade of CDK, the higher the prevalence of pterygium, the prevalence of pterygium without CDK was 2.8%, grade 1 9.3%, grade 2 20.2%; Barr Mongolian prevalence 10.2 %. The prevalence of CDK was significantly higher in those with CDK (16.3%) than in those without CDK (3.4%). The prevalence rates of Buryat Mongolian, Ewenki, Horqin Mongolian and Han were lower. Conclusion: The prevalence of clot-like corneal degeneration combined with pterygium in Hulunbeier region was significantly higher than that in non-CDM population. The nomads were higher than non-nomads in Hulunbeier area. The prevalences of different ethnic groups were different with those of grazing time and age , Ethnic and lifestyle related.
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