目的对醋酸地塞米松片HPLC法含量测定结果的不确定度进行分析和评价.方法按照2010版中国药典二部中醋酸地塞米松片含量测定方法进行测定,通过建立HPLC法测定醋酸地塞米松片含量的数学模型,找出影响不确定度的各种因素,进行分析和评估.结果本实验结果的扩展不确定度为1.3%,含量测定结果可表示为96.9%±1.3%.结论建立的方法可适用于HPLC法测定片剂含量的不确定度评估.“,”Objective:To evaluate the uncertainty of Dexamethasone Acetate tablets content determined by HPLC method.Method:According to the content determination of Dexamethasone Acetate in Chinese Pharmacopia (2010 edition),the factors affecting uncertainty were analysed and content uncertainty was evaluated by establishing mathematic model of content data. Results:The experimental results showed that the expanded uncertainty was 1.3% and the content was 96.9%±1.3%. Conclusion:The method we established applied to uncertainty evaluation of tablets content by HPLC.