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目的观察腹腔镜术联合道地通管汤灌肠、口服治疗输卵管阻塞性不孕的疗效。方法 160例输卵管阻塞性不孕患者按随机数字表法分为观察组和对照组各80例,两组均行腹腔镜下输卵管整复术,观察组术后给予道地通管汤一号方口服,二号方保留灌肠,对照组仅单纯手术治疗。比较两组受孕情况。结果随访2年,观察组受孕率为68.8%(55/80),明显高于对照组的43.8%(35/80),两组比较差异有统计学意义(P<0.05),其中观察组宫内受孕率为63.8%(51/80)明显高于对照组的27.5%(22/80),两组比较差异有统计学意义(P<0.05);观察组疗效好于对照组(P<0.05)。术后半年观察组未怀孕者43例,输卵管通畅62条(72.1%),通而不畅16条(18.6%),不通畅8条(15.9%);对照组未怀孕者63例,输卵管通畅56条(44.4%),通而不畅20条(15.9%),不通畅50条(39.7%);观察组输卵管通畅情况明显好于对照组(P<0.05)。结论道地通管汤联合腹腔镜术治疗输卵管阻塞性不孕,能有效改善盆腔局部血液循环,促进炎症吸收和粘连的纤维组织松解,利于输卵管管腔功能恢复,提高宫内受孕率。
Objective To observe the efficacy of laparoscopic combined with Dao Tong Tong Decoction for oral treatment of obstructive tubal infertility. Methods 160 cases of tubal obstruction infertility patients were divided into observation group and control group according to random number table method, 80 cases in each group, both groups underwent laparoscopic tubal plastic surgery, the observation group was given Dao Tong Tong Guan Tang Oral, enema retention on the 2nd, the control group only surgery alone. Comparison of two groups of pregnancy situation. Results The follow-up of 2 years showed that the conception rate of the observation group was 68.8% (55/80), significantly higher than that of the control group (43.8%, 35/80). There was significant difference between the two groups (P <0.05) The internal pregnancy rate was significantly higher in 63.8% (51/80) than that in control group (27.5%, 22/80), with significant difference between the two groups (P <0.05) ). In the six months after operation, 43 cases were not pregnant, 62 (72.1%) were tubal unobstructed, 16 (18.6%) were poor and 8 were unobstructed (15.9%). 56 cases (44.4%), 20 cases were not smooth (15.9%), 50 cases were not smooth (39.7%); observation group tubal patency was significantly better than the control group (P <0.05). Conclusion Dao Tong Tong Decoction combined with laparoscopic treatment of tubal obstruction infertility can effectively improve pelvic local blood circulation, promote inflammatory absorption and adhesion of fibrous tissue release, which will help tubal lumen functional recovery and improve intrauterine pregnancy rate.