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[目的]通过超声内镜结合细针穿刺活检(EUS-FNA)确定胰腺占位病变的性质,并评价该法对胰腺病变的诊断价值。[方法]入选经影像学检查示胰腺占位病变患者113例,对占位病变行EUS-FNA检查,评价EUSFNA的敏感性、特异性、准确性、阳性预测值、阴性预测值。[结果]113例患者均获得组织学或细胞学标本,穿刺成功率为100.0%。EUS-FNA对于胰腺占位病变诊断的准确性、特异性、敏感性、阳性预测值、阴性预测值分别为:89.4%、100.0%、85.8%、100.0%、33.3%。所有患者均未发生严重并发症。[结论]EUS-FNA对诊断胰腺占位性病变安全、有效,具有重要临床意义。
[Objective] To determine the nature of pancreatic lesions by endoscopic ultrasonography combined with fine needle aspiration biopsy (EUS-FNA) and to evaluate the diagnostic value of this method for pancreatic lesions. [Methods] One hundred and thirteen patients with pancreatic mass lesions were selected by imaging examination. EUS-FNA examination was performed on the lesions to evaluate the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of EUSFNA. [Results] The histological or cytological specimens of 113 patients were obtained. The successful rate of puncture was 100.0%. The accuracy, specificity, sensitivity, positive predictive value and negative predictive value of EUS-FNA for the diagnosis of pancreatic mass lesions were 89.4%, 100.0%, 85.8%, 100.0% and 33.3%, respectively. No serious complications occurred in all patients. [Conclusion] EUS-FNA is safe and effective in the diagnosis of pancreatic space-occupying lesions. It has important clinical significance.