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过敏性紫癜肾炎(Henoch-Schonlein Purpura Nephritis,HSPN)表现为弥漫性小血管炎,发病机制涉及免疫学异常(体液免疫异常为主,也涉及细胞免疫,有炎症细胞、细胞因子和炎症介质的参与);凝血与纤溶机制紊乱;基因多态性改变。肾脏病理上存在微血管与间质损害。1免疫学异常1.1体液
Henoch-Schonlein Purpura Nephritis (HSPN) is characterized by diffuse small vessel vasculitis and its pathogenesis involves immunological abnormalities (mainly humoral immune disorders, but also cellular immunity, involvement of inflammatory cells, cytokines and inflammatory mediators ); Coagulation and fibrinolysis disorders; changes in gene polymorphisms. Renal pathological microvascular and interstitial damage. 1 immunological abnormalities 1.1 body fluids