地方性克汀病的早期诊断问题,多年来一直是各国学者努力探索的重要课题.研究表明,人体的神经系统发育好坏的关键时期是从胚胎到出生期后2～3岁.地方性克汀病的精神系统损伤是对患者的主要危害之一,一旦成形,难于逆转。然而,患儿的早期症状既轻微,又缺乏特征性,与儿科常见疾病如佝偻病,营养不良易于混淆,常为家长及至临床医生所忽视,以致于在既往我们的流行病学调查中和临床上,难于对学龄令前的患儿作出肯定的诊断.国内外的经验认 The early diagnosis of endemic cretinism has been an important issue for scholars all over the world to explore for many years.The research shows that the critical period of human nervous system development is from embryo to postnatal period of 2 to 3 years It is one of the major harms of the patient’s nervous system damage to the tingopathy and, once formed, is difficult to reverse. However, the early symptoms in children are mild and lacking in character. They are easily confused with common pediatric diseases such as rickets and malnutrition. They are often overlooked by parents and clinicians, so that in the past in our epidemiological investigation and clinical , It is difficult to make a positive diagnosis of children before the school-age order