论文部分内容阅读
目的探讨清晨高血压对脑梗死复发的影响。方法急性脑梗死患者118例分为复发组58例和初发组60例。监测清晨血压(6:00~10:00)、24h动态血压情况,并测量颈动脉内膜中层厚度(IMT)和检查斑块情况。结果两组24-h动态血压监测结果无统计学差异(P>0.05),但脑梗死复发组清晨血压水平高于初发组(P<0.05)。复发组IMT大于初发组,不稳定斑块发生率也高于初发组(P<0.05)。结论清晨高血压可促进颈动脉粥样硬化的进程,加重颈动脉粥样硬化程度,并与脑梗死复发密切相关。有效控制清晨血压对预防脑梗死的复发有着重要的临床意义。
Objective To investigate the effect of early morning hypertension on the recurrence of cerebral infarction. Methods 118 patients with acute cerebral infarction were divided into 58 cases of recurrent group and 60 cases of initial group. Morning blood pressure (6: 00-10: 00) and ambulatory blood pressure (24h) were measured, carotid artery intima-media thickness (IMT) and plaque status were measured. Results There was no significant difference in 24-h ambulatory blood pressure monitoring between the two groups (P> 0.05). However, the early morning blood pressure was higher in recurrent patients with cerebral infarction than in the initial group (P <0.05). The IMT in the recurrent group was higher than that in the initial group, and the incidence of unstable plaque was also higher than that in the initial group (P <0.05). Conclusion Early morning hypertension can promote the process of carotid atherosclerosis and aggravate the degree of carotid atherosclerosis, which is closely related to the recurrence of cerebral infarction. Effective control of early morning blood pressure to prevent the recurrence of cerebral infarction has important clinical significance.