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目的探讨主动脉球囊反搏(intra-aortic balloon pump,IABP)治疗急性心肌梗死并心源性休克的临床疗效。方法 2008年2月至2011年3月间我院使用IABP治疗21例急性心肌梗死并心源性休克患者。观察应用IABP前后平均动脉压(MAP)、尿量、心率、多巴胺及多巴酚丁胺剂量变化。结果应用IABP治疗后患者的平均动脉压(MAP)升高、尿量增多、心率减慢、多巴胺及多巴酚丁胺剂量减少,治疗前后两组各指标变化幅度明显差异有统计学意义。结论急性心肌梗死并心源性休克患者予以IABP治疗,能增加冠状动脉灌注,改善心肌血供,降低左心室后负荷,从而改善心功能,治疗心源性休克。
Objective To investigate the clinical efficacy of intra-aortic balloon pump (IABP) in the treatment of acute myocardial infarction and cardiogenic shock. Methods From February 2008 to March 2011, 21 patients with acute myocardial infarction and cardiogenic shock were treated with IABP in our hospital. The changes of mean arterial pressure (MAP), urine output, heart rate, dopamine and dobutamine dose before and after application of IABP were observed. Results After treatment with IABP, mean arterial pressure (MAP) increased, urine output increased, heart rate slowed, and dopamine and dobutamine dose decreased. Before and after treatment, the change of each index was significantly different. Conclusions IABP treatment in patients with acute myocardial infarction and cardiogenic shock can increase coronary perfusion, improve myocardial blood supply and decrease left ventricular afterload, thereby improving cardiac function and treating cardiogenic shock.