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我院自1964～1987年应用激素,激素加环磷酰胺,激素加氮芥共治疗肾病综合征Ⅰ型185例,完全缓解115例复发33例(住院期间或出院后尿蛋白由阴性转为+++,且持续1周以上为复发),占28.6％,33例中激素减量过快7例,感冒、感染17例,劳累9例。20余年以来我们防止复发体会如下: 一、激素减量原则 (一) 对青年第一次入院,尿蛋白在15天内阴性者,第一次可减激素10～15mg,以后每2～3周减5mg,15mg以下1个月减2.5mg。
In our hospital from 1964 to 1987 the application of hormones plus cyclophosphamide, hormone plus nitrogen mustard in treating nephrotic syndrome type Ⅰ 185 cases, complete remission of 115 cases of relapse in 33 cases (during hospitalization or urinary protein excretion from negative to + ++, and for more than 1 week for recurrence), accounting for 28.6%, 7 cases of excessive reduction of hormone in 7 cases, cold, infection in 17 cases, fatigue in 9 cases. More than 20 years we have to prevent the recurrence of the following: First, the principle of hormone reduction (A) of young people for the first time, urinary protein negative within 15 days, the first can reduce hormone 10 ~ 15mg, after every 2 to 3 weeks less 5mg, 15mg the following month minus 2.5mg.