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患者女,51岁。右前臂无痛性紫红色结节4年余。皮损组织病理示:角化过度,真皮内肿瘤组织主要由成纤维样细胞和组织样细胞组成,可见较多不规则的出血性裂隙与囊腔,裂隙及囊腔周边无内皮细胞。免疫组织化学染色示:肿瘤细胞波形蛋白(Vimentin)和CD68阳性,而结蛋白(Desmin),CD34及S-100均阴性。结合临床表现、组织病理改变和免疫组织化学染色,诊断为动脉瘤样纤维组织细胞瘤。
Female patient, 51 years old. Right forearm painless purple red nodules more than 4 years. Pathological lesions showed: hyperkeratosis, intradermal tumor tissue mainly composed of fibroblast-like cells and tissue-like cells, showing more irregular hemorrhagic fissures and cysts, fissures and endothelial cells around the cysts. Immunohistochemical staining showed that tumor cells were positive for Vimentin and CD68 while negative for Desmin, CD34 and S-100. Combined with clinical manifestations, histopathological changes and immunohistochemical staining, diagnosis of aneurysm-like fibrous histiocytoma.