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目的探讨完整结肠系膜切除术(CME)与传统结肠癌根治术的中远期疗效。方法选取2011年8月至2013年12月在临颍县人民医院进行治疗的结肠癌患者180例,随机将其分为对照组90例和研究组90例。观察两组患者术中出血量,术后拔管时间、肛门排气时间、住院时间以术后开始进食时间。比较两组患者术中淋巴结切除情况、术后吻合口瘘及残端肿瘤残余情况。结果两组患者术中出血量,术后肛门排气、拔管、开始进食及住院时间比较差异均有统计学意义(P<0.05)。对照组患者术后吻合口瘘和残端肿瘤残余分别为8、14例,而研究组分别为2、5例,两组比较差异有统计学意义(P<0.05)。平均淋巴结数和阳性转移淋巴结数对照组显著高于研究组,差异有统计学意义(P<0.05)。结论在中远期的治疗中完整结肠系膜切除术较传统结肠癌根治术治疗效果好,对机体损伤小,并发症少。
Objective To explore the long-term therapeutic effect of complete mesorectal excision (CME) and conventional colon cancer radical mastectomy. Methods 180 patients with colon cancer who were treated in Linying People’s Hospital from August 2011 to December 2013 were randomly divided into control group (n = 90) and study group (n = 90). Two groups of patients were observed intraoperative blood loss, extubation time, anal exhaust time, hospitalization time to begin after eating time. Lymph node resection was compared between the two groups, and the residual anastomotic fistula and stump tumor after operation were compared. Results The blood loss, anal exhaust, extubation, food intake and hospital stay in two groups were statistically significant (P <0.05). In the control group, there were 8,14 cases of anastomotic fistula and residual stump tumor in the study group compared with 2,5 cases in the study group, respectively. There was significant difference between the two groups (P <0.05). The average number of lymph nodes and positive lymph node metastasis in the control group was significantly higher than that in the study group, with significant difference (P <0.05). Conclusion The treatment of complete mesorectal excision in the long-term treatment of colon cancer is more effective than traditional radical resection of colon cancer, less damage to the body, fewer complications.