目的:探讨妊娠中晚期合并阑尾炎的诊断与治疗策略。方法:对2008~2013年66例妊娠中晚期合并急性阑尾炎患者的诊断和治疗的资料进行分析。结果:66例患者中,手术治疗50例(75.76%),45例手术成功,成功率90.00%,5例出现先兆流产或先兆早产,失败率为10.00%;保守治疗16例(24.24%),7例出现先兆流产或先兆早产,失败率为43.75%。手术治疗的失败率明显低于保守治疗(χ2=9.281,P=0.002)。手术治疗患者住院8~29天,平均(12.38±4.11)天;保守治疗患者住院时间7~20天,两者住院时间无统计学差异(t=1.810,P=0.075)。结论:妊娠中晚期合并急性阑尾炎临床症状不典型,容易误诊,应及早明确诊断,尽早手术治疗,并预防术后并发症。 Objective: To investigate the diagnosis and treatment of appendicitis in the middle and late pregnancy. Methods: The data of 66 cases diagnosed and treated in the second trimester of pregnancy with acute appendicitis from 2008 to 2013 were analyzed. Results: Among the 66 patients, 50 cases were treated surgically (75.76%), 45 cases were successful, the success rate was 90.00%, 5 cases had threatened abortion or threatened premature delivery, the failure rate was 10.00%, conservative treatment was 16 cases (24.24%), Seven cases of threatened abortion or threatened premature delivery, the failure rate was 43.75%. The failure rate of surgical treatment was significantly lower than conservative treatment (χ2 = 9.281, P = 0.002). Surgical treatment of patients admitted to hospital for 8 to 29 days, an average of (12.38 ± 4.11) days; conservative treatment of patients hospitalized for 7 to 20 days, the length of stay between the two was no significant difference (t = 1.810, P = 0.075). Conclusion: The clinical manifestations of acute appendicitis in the second trimester of pregnancy are not typical and easily misdiagnosed. Early diagnosis should be made as soon as possible and the complications should be prevented as soon as possible.