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重危病人肾功能常急剧而不可予测地改变,因此,这类病人在采用低治疗指数的抗生素如氨基糖苷类时必须经常检测其浓度。由于多次静脉穿刺使采血困难,也可能导致暂时性贫血。儿科病人取多量血更是困难。本文用放射酶法检测氨基糖苷类抗生素,比较毛细血管血法及静脉血法的结果。血标本取自接受艮他霉素或丁胺卡那霉素治疗的病人。标本同时从手指尖及静脉穿刺取得。将标本(200μl)收集于两
Renal function in critically ill patients is often dramatically and unpredictably altered, and as such, these patients must frequently be tested for their use of low therapeutic index antibiotics such as aminoglycosides. Due to multiple venipuncture blood sampling difficulties, may also lead to temporary anemia. Pediatric patients take more blood is more difficult. In this paper, aminoglycoside antibiotics were detected by radioimmunoassay, comparing the results of capillary blood and venous blood. Blood samples were taken from patients receiving gentamicin or amikacin. Specimens from both the finger tip and venipuncture obtained. The specimen (200 μl) was collected in two