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为评价ｃｅｆｐｉｒａｎ 在治疗泌尿生殖系感染中的有效性和安全性，我们在多中心临床应用ｃｅｆｐｉｒａｎ开放性治疗各类泌尿生殖系感染３０例。用药剂量为１ｇ，静脉点滴，疗程５～７ｄ。结果：对急性单纯性尿路感染，使用ｃｅｆｐｉｒａｎ 后，治愈率为７８．６％ （１１／１４），有效率达１００％ （１４／１４）；对慢性复杂性尿路感染，治愈率为７０％（７／１０），有效率为８０％ （８／１０）。总治愈率为７３．３％ （２２／３０），总有效率为９０％ （２７／３０）。不良反应发生率为６．７％ 。细菌清除率为８２．１％ （２３／２８）。本研究结果表明，ｃｅｆｐｉｒａｎ 是治疗泌尿生殖系感染的一种有效、安全的新型抗菌药物。
To evaluate the efficacy and safety of cefpiran in the treatment of genitourinary infections, we have openly treated 30 patients with various urogenital infections in multicenter clinical cefpiran. Dose of 1g, intravenous drip, treatment 5 ~ 7d. Results: For acute simple urinary tract infection, the cure rate was 78.6% (11/14) and the effective rate was 100% (14/14) after using cefpiran. For chronic complicated urinary tract infection, the cure rate was 70 % (7/10), the effective rate was 80% (8/10). The total cure rate was 73.3% (22/30), the total effective rate was 90% (27/30). The incidence of adverse reactions was 6.7%. Bacterial clearance rate was 82.1% (23/28). The results of this study show that cefpiran is an effective and safe antimicrobial agent for the treatment of genitourinary infections.