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报道日本国秋田大学医学部附属临床医院中央放射线部诊疗技师的外周血淋巴细胞染色体畸变的适应性反应研究。该部有诊疗技师18名,均为男性,年龄25—59岁,职业工龄5—20年。累积吸收剂是0.02—0.22 mSv/月(1971.3—1991.2,1971.2以前的剂量未作估算),以染色体畸变为观察指标。结果表明,职业受照者的淋巴细胞染色体畸变率显著高于对照组(P<0.05)。当职业受照者的淋巴细胞经1.5 Gy~(60)Coγ射线体外照射(剂量率0.30 Gy/min)后,染色体型畸变率明显低于非职业人员离体血接受同样条件照射的结果,而染色单体型畸变率则未见降低,表明职业受照者的淋巴细胞染色体型畸变率存在适应性反应而染色单体型畸变率则未发现适应性反应。
Reported that Japan’s Akita University Medical Center Affiliated Hospital of Central Radiology clinic technicians peripheral blood lymphocyte chromosome aberrations in adaptive response. The Department has 18 medical technicians, both men, aged 25-59 years, working years of service 5-20 years. Cumulative absorbance was 0.02-0.22 mSv / month (1971.3-1991.2, 1971.2 before the dose was not estimated), the chromosomal aberration as an indicator. The results showed that occupational exposure of lymphocyte chromosome aberration was significantly higher than the control group (P <0.05). When the occupationally irradiated lymphocytes were exposed to 1.5 Gy ~ (60) Co γ-rays in vitro (dose rate 0.30 Gy / min), the chromosome aberration rate was significantly lower than that of non-professional off-line blood receiving the same conditions Chromosome haplotype aberration rate was not reduced, indicating that occupational exposure to lymphocyte chromosome aberration rate of adaptive response and the chromatid aberration rate was found no adaptive response.