论文部分内容阅读
随着左氧氟沙星临床应用范围的不断扩大,其毒副反应的报道日益增多。为了更好地促进安全用药,就相关报道进行综述。笔者通过查阅和复习相关文献,对近年来左氧氟沙星的不良反应进行了归纳与综述:左氧氟沙星的主要毒副反应有恶心、呕吐、腹痛、腹泻等消化道症状;焦虑、失眠、头昏、耳鸣、记忆力减退和意识丧失等神经和精神症状;过敏性皮疹、静脉炎和过敏性休克;偶见白细胞减少及低血糖等。左氧氟沙星的毒副反应可发生于用药后的不同时间段,涉及到多个系统的多个器官,重者可危及生命。用药前必须详细询问有无药物过敏史,规范使用剂量,控制静滴速度,并密切观察患者反应,方能确保临床用药安全。
With the continuous expansion of the clinical application of levofloxacin, the reports of its toxicity have been increasing. In order to better promote the safe use of drugs, the related reports are reviewed. The author reviews and reviews the related literature and summarizes the adverse reactions of levofloxacin in recent years: The main side effects of levofloxacin are nausea, vomiting, abdominal pain, diarrhea and other gastrointestinal symptoms; anxiety, insomnia, dizziness, tinnitus, memory Diminished and loss of consciousness and other neurological and psychiatric symptoms; allergic rash, phlebitis and anaphylactic shock; occasional leukopenia and hypoglycemia. Levofloxacin toxicity can occur in different time periods after treatment, involving multiple systems of multiple organs, severe cases can be life-threatening. Medication before the drug must be asked in detail the history of allergies, regulate the use of dose, intravenous infusion rate control, and close observation of patient response, to ensure the safety of clinical medication.