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目的探讨他汀类药物对老年冠状动脉粥样硬化性心脏病患者血脂的影响。方法选择2006年7月至2011年7月在我院心内科住院治疗使用他汀类药物进行冠状动脉粥样硬化性心脏病调脂治疗的的132例冠状动脉粥样硬化性心脏病患者为研究对象,12周后对所有患者血脂进行随访,比较治疗前后冠状动脉粥样硬化性心脏病患者的血脂情况。结果他汀类药物治疗后,总胆固醇由(5.26±0.34)mmol/L降至(4.67±0.36)mmol/L,三酰甘油(TG)(2.02±0.18)mmol/L降至(1.64±0.22)mmol/L,低密度脂蛋白(3.32±0.26)mmol/L降至(2.64±0.05)mmol/L,高密度脂蛋白(1.17±0.17)mmol/L降至(1.51±0.30)mmol/L,治疗前后差异有统计学意义(P<0.05)。结论他汀类药物可以明显降低老年冠状动脉粥样硬化性心脏病患者的高脂,值得在临床中推广应用。
Objective To investigate the effects of statins on blood lipids in elderly patients with coronary atherosclerotic heart disease. Methods From July 2006 to July 2011 in our hospital cardiology inpatient treatment of coronary heart disease with statins lipid-lowering treatment of coronary heart disease patients with atherosclerotic heart disease 132 patients After 12 weeks, all patients were followed up for blood lipids, compared with before and after treatment of coronary atherosclerotic heart disease in patients with lipid profile. Results After treatment with statins, total cholesterol decreased from (5.26 ± 0.34) mmol / L to (4.67 ± 0.36) mmol / L, and triglyceride (TG) decreased from 2.02 ± 0.18 mmol / L to 1.64 ± 0.22 L to (2.64 ± 0.05) mmol / L and (1.17 ± 0.17) mmol / L to (1.51 ± 0.30) mmol / L, Before and after treatment, the difference was statistically significant (P <0.05). Conclusion Statins can significantly reduce the elderly patients with coronary atherosclerotic heart disease, it is worth in the clinical application.