先天性血浆凝血酶元(因子Ⅱ)缺乏症极罕见,自1947年发现迄今,文献报导过十余例。先天性血浆因子Ⅶ缺乏症也极少见,于1951年发现,发病率约1/50万,至1967年止报导过60例。均属常染色体不完全隐性遗传的出血性疾病。最近我院发现一例获得性血浆因子Ⅱ、Ⅶ联合缺乏的出血性疾病,报告如下:患者:张××,女性,41岁,汉族,已婚,河北省房山县人。因肉眼血尿,皮肤瘀 Congenital thromboplastin (factor Ⅱ) deficiency is extremely rare, since 1947 found so far, the literature reported more than a dozen cases. Congenital plasma factor Ⅶ deficiency is also rare, found in 1951, the incidence of about 1,500,000, reported in 1967 reported 60 cases. Are autosomal recessive hereditary hemorrhagic disease. Recently, we found a case of acquired plasma factor Ⅱ, Ⅶ combined lack of hemorrhagic disease, the report is as follows: Patients: Zhang × ×, female, 41 years old, Han nationality, married, Fangshan County, Hebei Province. Due to gross hematuria, skin stasis