论文部分内容阅读
目的探讨肺炎支原体肺炎患儿免疫功能与其病情的相关性。方法采用流式细胞术和免疫散射比浊法检测34例肺炎支原体肺炎患儿外周血T淋巴细胞亚群变化和免疫球蛋白M(IgM)、IgG、IgA以及补体C3、C4水平,记录患儿使用大环内酯类药物后发热天数及恢复期肺炎胸片吸收评价量表分数,分析免疫指标与后两者的相关性。结果发热天数与血清IgM、IgG水平均呈正相关(r=0.380、0.335,P<0.05),恢复期肺部胸片感染灶严重度与CD8~+T淋巴细胞比例呈正相关(r=0.354,P<0.05)。结论肺炎支原体肺炎患儿免疫功能与发热天数及恢复期胸片吸收情况存在相关性,对临床预后有提示作用。
Objective To investigate the correlation between immune function and its condition in children with Mycoplasma pneumoniae pneumonia. Methods The changes of T lymphocyte subsets, immunoglobulin M (IgM), IgG, IgA and complement C3 and C4 in peripheral blood of 34 children with mycoplasma pneumoniae pneumonia were detected by flow cytometry and immunomagnetic turbidimetry. The use of macrolides days after fever and recovery of pneumonia chest X-ray absorption rating scale scores, analysis of immune indicators and the latter two correlation. Results The days of fever were positively correlated with serum IgM and IgG levels (r = 0.380,0.335, P <0.05). The severity of lung chest X-ray lesions at recovery stage was positively correlated with the proportion of CD8 + T lymphocytes (r = 0.354, P <0.05). Conclusions There is a correlation between immune function and days of fever and absorption of chest X-ray in children with mycoplasma pneumoniae pneumonia.