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胆管癌可切除率很低(20%～30%),有时即使手术切除,也不能根治。体外放疗因剂量受限(照射区有重要脏器),效果往往欠佳。但术中放疗(IORT)则无此弊端,因治疗时可将邻近正常组织结构推开加以保护,使其在免受或少受照射的情况下,增大对病灶的照射剂量。迄今仅有6则小宗胆管癌IORT的报导,这方面尚缺乏有价值的资料。本文作者总结了5年间应用中电压IORT治疗胆管癌的经验。
The resectable rate of cholangiocarcinoma is very low (20% to 30%), and sometimes it cannot be cured even after surgical resection. In vitro radiotherapy due to dose limitations (important organs in the irradiated area), the effect is often poor. However, intraoperative radiotherapy (IORT) has no such drawbacks, because during treatment, the adjacent normal tissue structure can be opened and protected, so that it can increase the irradiation dose to the lesion under the condition of being protected from or less exposed to radiation. So far there have been only 6 reports of IORT cholangiocarcinoma, which lacks valuable information. The authors of this article summarized the experience of using medium-voltage IORT for the treatment of cholangiocarcinoma in 5 years.