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目的:评价立体定向放射治疗肺癌脑转移瘤的效果。方法:收集2003年1月至2006年5月肺癌脑转移病人在我院进行立体定向放射治疗共100例进行回顾性分析,单次靶区周边剂量为8Gy,总剂量为32—48Gy,分4～6次完成。结果:完全缓解率为26%(26/100),部分缓解率为68%(68/100),无效6%(6/100),生存时间超过半年者82例,半年生存率为82%;生存时间超过1年者46例,1年生存率为46%。结论:立体定向放射治疗对肺癌脑转移瘤有确切的疗效,配合全脑照射,可以延长患者寿命,提高生存质量。
Objective: To evaluate the effect of stereotactic radiotherapy on brain metastases of lung cancer. METHODS: A total of 100 patients with brain metastases from lung cancer undergoing stereotactic radiotherapy in our hospital from January 2003 to May 2006 were retrospectively analyzed. The peripheral dose of single target area was 8 Gy and the total dose was 32-48 Gy. ~ 6 times to complete. Results: The complete remission rate was 26% (26/100), the partial remission rate was 68% (68/100), the ineffective 6% (6/100), the survival time was more than half a year, 82 cases, and the half year survival rate was 82%. 46 cases survived more than 1 year, 1-year survival rate was 46%. Conclusion: Stereotactic radiotherapy has the exact effect on brain metastases of lung cancer. Combined with whole brain irradiation, it can prolong the life of patients and improve the quality of life.