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由“生脉散”(人参麦冬五味子)研制成功的生脉液,临床用于感染性休克等取得较好疗效,本文从抗炎及免疫角度对其药理作用进行了初步研究,结果如下。一、生脉注射液的抗炎作用 1、生脉液对毛细血管通透性的影响①生脉液10ml/kgi、px5天,按Northover法测定小鼠腹部注射组织胺后局部皮肤内伊文斯兰的兰染级别,结果表明生脉液对组织胺引起的毛细血管通透性有非常显著的抑制作用,其抑制强度与0.5mg/kg盐酸肾上腺素的作用无明显差异。
From “Shengmaisan” (ginseng Ophiopogon japonicus) developed Shengmai, clinically used for septic shock and achieved good effect, this article from the perspective of anti-inflammatory and immune pharmacological effects of a preliminary study, the results are as follows. First, the anti-inflammatory effect of Shengmai injection 1, Shengmai on capillary permeability ① Shengmai 10ml / kgi, px5 days, according to the Northover method to determine the mouse abdominal injection of histamine local skin Evans Blue dye level, the results show that Shengmai on histamine induced capillary permeability has a very significant inhibitory effect of its inhibitory strength and 0.5mg / kg of epinephrine hydrochloride no significant difference in the role.