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在以前的研究中,作者曾发现一些非淋巴组织(肝、肾、肺和心脏)的细胞、细胞核和染色质含有大量的非组蛋白(NHP),而在淋巴组织(胸腺和脾)的相应部分,NHP的含量很低。并认为对辐射高度敏感的淋巴细胞在辐照(0.5～4Gy)后数小时出现分裂间期死亡是与NHP的缺乏有密切关系。本文为了弄清对辐射敏感或不敏感的细胞核构造,就要获得关于细胞核NHP的补充资料。获得的证据表明,胸腺和脾脏的细胞核紧结合NHP比肝、肾、肺和心的细胞核紧结合NHP少得多。
In previous studies, the authors have found that some of the non-lymphoid tissues (liver, kidney, lung and heart) contain large numbers of non-histone (NHP) cells, nuclei and chromatin, whereas in lymphoid tissue (thymus and spleen) In part, NHP content is low. It is considered that there is a close relationship with the lack of NHP in radiation-sensitive lymphocytes that appear interphase death several hours after irradiation (0.5-4 Gy). In this paper, in order to clarify the radiation-sensitive or insensitive to the nuclear structure, it is necessary to obtain additional information on the nuclear NHP. Evidence obtained indicates that tight junctions of NHPs in the thymus and spleen nuclei are much less associated with NHPs than in the nuclei of the liver, kidney, lung and heart.