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目的 探讨肠易激综合征 (IBS)活动期及缓解期的血浆 5 羟色胺 (5 HT)及其代谢产物 5 羟吲哚乙酸浓度的差异。方法 参照罗马Ⅱ诊断标准 ,选取腹泻型IBS患者 14例及便秘型 11例 ,正常对照组 12例。用高效液相色谱电化学法测定IBS患者缓解期和活动期及健康对照组的血浆 5 HT
Objective To investigate the difference of plasma 5-hydroxytryptamine (5 HT) and its metabolite 5-hydroxyindole-acetic acid concentration in the active and remission stages of irritable bowel syndrome (IBS). Methods According to the diagnostic criteria of Rome Ⅱ, 14 cases of diarrhea-predominant IBS and 11 cases of constipation were selected, and 12 cases of normal control group. Determination of plasma 5 HT in patients with IBS during remission and active phase and healthy controls by high performance liquid chromatography-electrochemical method