目的:观察激光周边虹膜切除术(laser peripheral iridoplasty,LPIP)治疗房角广泛粘连的原发性急性闭角型青光眼(primary actue angle-closure glaucoma,PAACG)的长期效果。方法:回顾性总结原发性闭角型青光眼(primary angle-closure glaucoma,PACG)急性发作后房角广泛粘连33例33眼的LPIP治疗的远期效果,主要观察患者眼压控制情况及房角粘连的变化。以不使用或使用不超过3种局部降眼压药物,眼压≤21mmHg视为眼压控制。结果:患者24眼随访21～37mo,眼压成功控制,其中15眼使用1～2种局部降眼压药物;9眼因眼压控制不满意最终行小梁切除术,其中6眼于LPIP后3d内手术治疗,另3眼分别于LPIP后18,42d;9mo手术治疗。LPIP治疗后短期内27眼房角粘连不同程度开放,6～12mo后,6眼的房角粘连程度较治疗早期扩大。LPIP治疗后3眼出现核性白内障,其中1眼于激光后3a行白内障超声乳化术。结论:LPIP是治疗房角广泛粘连的急性闭角型青光眼的有效手段,但部分患者在激光后不同时间出现眼压升高,房角再次粘连,应定期检查。 Objective: To observe the long-term effect of laser peripheral iridoplasty (LPIP) in the treatment of primary actue angle-closure glaucoma (PAACG) with extensive adhesion. Methods: To retrospectively review the long-term effects of LPIP in 33 cases (33 eyes) of primary angle-closure glaucoma (PACG) posterior chamber angle extensively retrospectively. Mainly observe the intraocular pressure control and angle Changes in adhesion. To not use or use no more than three kinds of local intraocular pressure lowering drugs, intraocular pressure ≤ 21mmHg as intraocular pressure control. RESULTS: Twenty-four eyes were followed up for 21-37 months. Intraocular pressure was successfully controlled. One or two topical intraocular hypotensive agents were used in 15 eyes. Nine eyes were treated with intraocular pressure (IOP) and were not satisfied with the final trabeculectomy. Six of them were treated with LPIP 3d surgical treatment, the other three were 18,182 days after LPIP; 9mo surgical treatment. Shortly after the treatment of LPIP, 27 eyes had anterior chamber angle adhesions open to varying degrees, 6 to 12 months later, the 6 eyes had a greater degree of adhesion than those treated early. In the three eyes after LPIP, nuclear cataracts were found. Among them, 1 patient underwent cataract phacoemulsification with 3a after laser irradiation. Conclusions: LPIP is an effective method for the treatment of acute angle-closure glaucoma with extensive adhesion in the corners of the corner. However, in some patients, intraocular pressure (IOP) rises at different time after laser exposure and adhesions again. The angle should be checked regularly.