在慢性乙型肝炎临床诊疗过程中,部分患者黄疸下降到一定程度就持久不退,总胆红素为100~150μmol/L,病程超过3个月,谓之残留黄疸,又称顽固性黄疸、难治性黄疸。此类患者血中胆红素长期升高,肝脏负担重,发生肝硬化的概率比常人明显增高,给患者带来精神痛苦和经济负担,迅速消退黄 In the clinical diagnosis and treatment of chronic hepatitis B, some patients jaundice dropped to a certain extent, durable, total bilirubin 100 ~ 150μmol / L, duration of more than 3 months, that the residual jaundice, also known as intractable jaundice, Refractory jaundice. Such patients with long-term elevated serum bilirubin, the liver burden, the probability of occurrence of cirrhosis was significantly higher than normal, bringing mental anguish and financial burden on the patient, quickly dissipate yellow