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目的探讨垂体后叶素联合酚妥拉明治疗支气管扩张大咯血的有效性及安全性。方法选取山西省原平市第一人民医院2012年8月—2015年8月收治的支气管扩张大咯血患者80例,按照随机数字表法分为对照组和试验组,各40例。对照组仅采用垂体后叶素治疗,试验组在对照组基础上联合酚妥拉明治疗。比较两组患者的治疗效果及不良反应发生情况。结果治疗后,试验组治疗总有效率高于对照组,差异有统计学意义(χ2=8.51,P<0.05);试验组不良反应发生率低于对照组,差异有统计学意义(χ2=4.31,P<0.05)。结论垂体后叶素联合酚妥拉明治疗支气管扩张大咯血疗效显著,且不良反应少,值得临床推广应用。
Objective To investigate the efficacy and safety of pituitrin combined with phentolamine in the treatment of bronchiectasis. Methods Eighty patients with bronchiectasis and hemoptysis admitted to the First People’s Hospital of Yuanping City of Shanxi Province from August 2012 to August 2015 were divided into control group and experimental group according to the random number table. The control group only treated with pituitrin, the experimental group on the basis of the control group combined with phentolamine treatment. The therapeutic effects and adverse reactions of the two groups were compared. Results After treatment, the total effective rate in the experimental group was significantly higher than that in the control group (χ2 = 8.51, P <0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group (χ2 = 4.31 , P <0.05). Conclusions Pituitrin combined with phentolamine treatment of bronchiectasis hemoptysis significant effect, and fewer adverse reactions, it is worthy of clinical application.