目的探讨淋巴瘤合并静脉血栓(venous thromboembolism,VTE)的临床特征。方法回顾性分析11例成人淋巴瘤合并VTE患者临床资料。结果 11例淋巴瘤并VTE患者中,2例为霍奇金淋巴瘤,9例为非霍奇金淋巴瘤;3例以VTE为首发症状,7例于化疗第2~3周期诊断VTE,1例确诊淋巴瘤2a后使用沙利度胺治疗期间发生VTE;肢体VTE 8例(其中1例为中心静脉置管相关性血栓),上腔静脉综合征2例,急性肺动脉栓塞1例。结论 VTE可能是淋巴瘤的首要表现,化疗及深静脉置管等是淋巴瘤并发血栓的重要诱因。 Objective To investigate the clinical characteristics of lymphoma with venous thromboembolism (VTE). Methods The clinical data of 11 adult lymphoma patients with VTE were analyzed retrospectively. Results Of the 11 cases of lymphoma and VTE, 2 were Hodgkin’s lymphoma and 9 were non-Hodgkin’s lymphoma. VTE was the first symptom in 3 cases and VTE was diagnosed in 2 of 3 cycles of chemotherapy Cases of lymphoma after the diagnosis of lymphoma with thalidomide occurred during VTE; 8 cases of limb VTE (1 case of central venous catheter-related thrombosis), superior vena cava syndrome in 2 cases, 1 case of acute pulmonary embolism. Conclusions VTE may be the primary manifestation of lymphoma. Chemotherapy and deep vein catheterization are important inducing factors of thrombus in lymphoma.