论文部分内容阅读
目的探讨泮托拉唑预防急性脑梗死并发应激性溃疡的不良反应。方法收集2010年7月至2013年6月我院收治的急性脑梗死并发应激性溃疡120例患者资料,随机分为观察组和对照组,各60例。两组均给予常规治疗,对照组患者在常规治疗的基础上给予法莫替丁,观察组患者在常规治疗的基础上给予泮托拉唑。比较两组患者不良反应发生率。结果观察组患者的不良反应发生率为18.3%,明显低于对照组的48.3%,差异有统计学意义(P<0.05)。结论泮托拉唑可减少急性脑梗死并发应激性溃疡的发生和降低上消化道出血风险。
Objective To investigate the adverse effects of pantoprazole on acute cerebral infarction complicated by stress ulcer. Methods The data of 120 patients with acute cerebral infarction complicated with stress ulcer admitted in our hospital from July 2010 to June 2013 were randomly divided into observation group and control group, with 60 cases in each group. Both groups were given routine treatment. Patients in the control group were given famotidine on the basis of routine treatment. The patients in the observation group were given pantoprazole on the basis of routine treatment. Adverse reactions in two groups were compared. Results The incidence of adverse reactions in the observation group was 18.3%, which was significantly lower than that in the control group (48.3%), the difference was statistically significant (P <0.05). Conclusion Pantoprazole can reduce the incidence of acute cerebral infarction complicated by stress ulcer and reduce the risk of upper gastrointestinal bleeding.