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目的 观察不同疗程甘露醇对急性脑出血患者的疗效影响。方法 应用 2 0 %甘露醇治疗急性脑出血患者 16 3例 ,观察组 85例 ,疗程 30天 ,对照组 78例 ,疗程 10天。在治疗前、治疗后 10天、30天、90天分别进行改良爱丁堡 -斯堪的那维亚评分 (MESSS) ,在 30天、90天加用日常生活能力评价 (ADL)。结果 两组在治疗后 10天的显效率、总有效率比较无显著差异 (P>0 .0 5 ) ,在治疗后 30天比较有显著差异 (P<0 .0 5 )。两组在治疗后 30天、90天的 ADL 比较有显著差异 (P<0 .0 5 )。结论 延长甘露醇的治疗时间能使脑出血患者得到较快的恢复 ,从而最大程度地改善生活质量。
Objective To observe the effect of different courses of mannitol on patients with acute cerebral hemorrhage. Methods A total of 16 3 patients with acute cerebral hemorrhage were treated with 20% mannitol and 85 patients in the observation group. The course of treatment was 30 days. In the control group, 78 patients were treated for 10 days. The modified Edinburgh-Scandinavian score (MESSS) was administered before treatment, 10 days, 30 days and 90 days after treatment, and ADL was added at 30 days and 90 days. Results The effective rate and total effective rate of the two groups after 10 days of treatment showed no significant difference (P> 0.05), and there was significant difference between the two groups after 30 days of treatment (P <0.05). There was a significant difference in ADL between the two groups at 30 days and 90 days (P <0.05). Conclusion Prolonging the duration of mannitol treatment can result in a faster recovery of patients with ICH, thus maximizing the quality of life.