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目的:探讨平均红细胞体积(MCV)和红细胞体积分布宽度(RDW)在骨髓增生异常综合征(MDS)和缺铁性贫血(IDA)鉴别诊断中的应用价值和意义。方法:ABX MICROS60自动血液分析仪检测23例MDS患者和31例IDA患者的MCV、RDW值。结果:MDS和IDA患者的MCV分别为(103.1±10.8)fl和(73.7±9.6)fl,差异有统计学意义(P<0.01)。而MDS和IDA患者的RDW分别为(18.7±4.4)和(17.6±2.8)均高于正常参考值,2组间数据比较,差异无统计学意义(P>0.05)。MDS患者MCV、RDW增高,IDA患者MCV减低、RDW增高。结论:MCV、RDW的变化在MDS和IDA鉴别诊断中有较高的应用价值。
Objective: To investigate the value and significance of mean corpuscular volume (MCV) and erythrocyte bulk density (RDW) in the differential diagnosis of myelodysplastic syndrome (MDS) and iron deficiency anemia (IDA). Methods: The MCV and RDW values of 23 patients with MDS and 31 patients with IDA were detected by ABX MICROS60 automatic hematology analyzer. Results: The MCV of patients with MDS and IDA were (103.1 ± 10.8) fl and (73.7 ± 9.6) fl, respectively, with significant difference (P <0.01). However, the RDW in MDS and IDA patients were (18.7 ± 4.4) and (17.6 ± 2.8), respectively, which were higher than the normal reference values. There was no significant difference in data between the two groups (P> 0.05). MDS patients MCV, RDW increased IDA MCV decreased, RDW increased. Conclusion: The changes of MCV and RDW have high value in the differential diagnosis of MDS and IDA.