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中枢神经系统一旦受到有害多因素侵袭,血脑屏障被破坏,可引起局部或广泛的血脑屏障通透性改变。脑外伤、脑肿瘤均可导致血脑屏障开放。掌握严重颅脑损伤时血脑屏障开放的范围和时间,对临床治疗中避免使用加重脑组织损伤的药物非常重要。血脑屏障的控制可能在治疗脑肿瘤及中枢神经系统基因疾病方面起重要作用。有关血脑屏障的中枢神经系统药物与放射影像学研究对临床诊断和治疗具有实用价值。
Once the central nervous system is attacked by harmful multi-factors, the blood-brain barrier is destroyed, causing local or extensive changes in the permeability of the blood-brain barrier. Brain trauma, brain tumors can lead to the opening of the blood-brain barrier. Mastering the extent and timing of blood-brain barrier opening during severe craniocerebral injury is important for avoiding the use of medications that aggravate brain tissue damage during clinical treatment. The control of the blood-brain barrier may play an important role in the treatment of brain tumors and diseases of the central nervous system. Central nervous system drugs and radiological studies on the blood-brain barrier have clinical value in clinical diagnosis and treatment.