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为提高对男性狼疮肾炎 (ML N)和女性狼疮肾炎 (FL N)差异的认识 ,减少临床误诊 ,本组对 6 2例ML N与 6 2例随机选择的 FL N的临床表现、实验室检查、病理、疗效及预后进行了回顾性分析。结果显示 ML N和FL N的发病年龄分布不同 ,SL E中 ML N发生率高 (P<0 .0 5 ) ,较易误诊 (P<0 .0 5 )和延迟诊断 (P<0 .0 5 ) ,且关节痛较 FL N少见 ,抗核抗体阳性率亦明显低于 FL N(P<0 .0 1) ,其他各项免疫指标和肾外临床表现与 FL N相比无明显差异。 ML N对治疗反应差 (P<0 .0 5 ) ,病情恶化者较 FL N多见。因此临床上应对 ML N给予高度重视。
To improve understanding of the differences between male and female lupus nephritis (MLN) and female patients with lupus nephritis (FLN) and to reduce the clinical misdiagnosis, this group of 62 cases of ML N and 62 cases of randomly selected FL N clinical manifestations, laboratory tests , Pathology, curative effect and prognosis were retrospectively analyzed. The results showed that the distribution age of ML N and FL N was different. The incidence of ML N in SL E was higher (P <0.05), misdiagnosis (P <0.05) and delayed diagnosis (P <0. 0) 5). Arthritis pain was more rare than FLN, and the positive rate of antinuclear antibody was also significantly lower than that of FLN (P <0.01). There was no significant difference in other immune indexes and extrarenal clinical manifestations compared with FLN. ML N response to treatment was poor (P <0.05), worsening conditions more common than FL N. Therefore, the clinical response to ML N give great importance.