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目的观察马来酸桂哌齐特联合依达拉奉治疗急性脑梗死的疗效。方法将80例急性脑梗死患者随机分为2组。治疗组40例采用马来酸桂哌齐特联合依达拉奉静脉滴注;对照组40例采用复方丹参加CDPC注射液静脉滴注。疗程均为14d。观察2组临床疗效及治疗前后神经功能缺损评分。结果总有效率治疗组为90.0%,对照组为66.7%,2组比较,差异有显著性意义(p<0.05);2组治疗后神经功能缺损评分均有不同程度恢复,治疗后与治疗前比较,差异均有显著性意义(p<0.05);治疗后治疗组与对照组比较,差异有显著性意义(p<0.05)。结论马来酸桂哌齐特联合依达拉奉治疗急性脑梗死疗效高、副作用小。
Objective To observe the curative effect of cinepazide maleate and edaravone in the treatment of acute cerebral infarction. Methods Eighty patients with acute cerebral infarction were randomly divided into two groups. 40 cases in the treatment group were treated with cinepazide maleate and edaravone intravenously; 40 cases in the control group were given intravenous drip of CDDP injection. Treatment are 14d. The clinical efficacy and neurological deficit scores of two groups were observed before and after treatment. Results The total effective rate was 90.0% in the treatment group and 66.7% in the control group. There was significant difference between the two groups (p <0.05). The neurological deficit scores of the two groups recovered to different degrees after treatment, (P <0.05). After treatment, the difference between the treatment group and the control group was significant (p <0.05). Conclusion Cinepazide maleate combined with edaravone in the treatment of acute cerebral infarction with high efficacy and small side effects.