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目的:评价布地奈德福莫特罗粉吸入剂与阿奇霉素联用对支气管哮喘患者症状改善的疗效。方法:选取2012年4月—2015年4月间收治的支气管哮喘患者86例,根据治疗方法将其分为观察组和对照组,每组43例;观察组患者给予布地奈德福莫特罗粉吸入剂与阿奇霉素联用治疗,对照组患者则给予单用布地奈德福莫特罗粉吸入剂治疗,评价两组患者治疗后的总有效率、临床各症状改善情况及不良反应的发生率。结果:观察组患者治疗后的总有效率为95.34%高于对照组为72.09%(P<0.05);咳嗽消失时间为(3.5±0.8)d,呼吸困难缓解时间为(2.2±0.6)d,肺部哮鸣音消失时间为(3.1±0.6)d均优于对照组分别为(5.9±0.7)d(、3.7±0.8)d和(7.0±1.4)d;临床各症状消退时间明显短于对照组(P<0.05);观察组患者用药期间不良反应的发生率为2.34%低于对照组为11.64%(P<0.05)。结论:采用布地奈德福莫特罗粉吸入剂与阿奇霉素联用治疗支气管哮喘患者,能有效改善患者的临床各症状。
OBJECTIVE: To evaluate the efficacy of combination of formoterresin and budesonide formoterol inhaler in the treatment of patients with bronchial asthma. Methods: Eighty-six patients with bronchial asthma were selected from April 2012 to April 2015, and divided into observation group and control group according to the treatment method, 43 cases in each group. The patients in observation group were given budesonide formoterol Powder inhalation combined azithromycin treatment, while patients in the control group were given budesonide formoterol powder inhalation alone, the evaluation of the two groups of patients after treatment, the total effective rate, the clinical symptoms and the incidence of adverse reactions . Results: The total effective rate of observation group was 95.34%, which was significantly higher than that of control group (72.09%, P <0.05). The duration of cough disappearance was (3.5 ± 0.8) days and the duration of respiratory distress was (2.2 ± 0.6) The duration of the disappearance of lung wheeze was (3.1 ± 0.6) d, which was significantly lower than that of the control group (5.9 ± 0.7) d (3.7 ± 0.8) days and (7.0 ± 1.4) days respectively. (P <0.05). The incidence of adverse reactions in the observation group was 2.34% lower than that in the control group (P <0.05). CONCLUSIONS: The use of budesonide formoterol powder inhalers combined with azithromycin in the treatment of patients with bronchial asthma can effectively improve the clinical symptoms of patients.