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目的探讨急性冠脉综合征(ACS)患者血清肌钙蛋白I(cTnI)和超敏C一反应蛋白(hs-CRP)测定的临床意义。方法采用化学发光法和免疫透射比浊法对75例ACS患者进行了血清肌钙蛋白I(cTnI)和超敏C一反应蛋白水平测定,并与30名正常健康人作比较。结果ACS组的cT-nI和hs-CRP含量均显著高于对照组(P<0.01),ACS组中,急性心肌梗死(AMI)组的cTnI和hs-CRP水平均显著高于不稳定型心绞痛(UAP)组(P<0.01)。结论cTnI和hs-CRP的增高与急性冠脉综合征密切相关,为临床提供重要的参考依据。
Objective To investigate the clinical significance of serum cTnI and hs-CRP in patients with acute coronary syndrome (ACS). Methods Serum troponin I (cTnI) and hypersensitive C-reactive protein levels were measured in 75 patients with ACS by chemiluminescence and immunoturbidimetry and compared with 30 healthy controls. Results The levels of cT-nI and hs-CRP in ACS group were significantly higher than those in control group (P <0.01). In ACS group, the levels of cTnI and hs-CRP in AMI group were significantly higher than those in unstable angina pectoris group (UAP) group (P <0.01). Conclusions The increase of cTnI and hs-CRP is closely related to acute coronary syndrome, providing an important reference for clinical practice.