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细胞免疫的转移现象.早在40年代Landstine和Chase发现致敏豚鼠的淋巴细胞能把迟发型变态反应转移给非致敏的豚鼠,从而得以证实。1949年Law-rence将结核菌素(OT)反应阳性者的活白细胞注入对结核菌素反应阴性的人体后,则能迅速出现结核菌素皮试阳性反应。1955年Lawrence进一步发现,白细胞用水溶解或经冻融破碎,其提取物仍具有转移迟发型变态反应的作用,这种能将供体的某种特定的细胞免疫功能特异地转给受体,使受体也具有该种细胞免疫力的物质即称为转移因子〔transfer factor(TF)〕。
The phenomenon of cellular immune transfer. As early as the 40’s Landstine and Chase found that sensitized guinea pig lymphocytes can delay the transfer of allergic reactions to non-sensitized guinea pigs, which was confirmed. In 1949 Law-rence tuberculin (OT) -positive live white blood cells injected into the tuberculin-negative human body, you can quickly appear tuberculin skin test positive reaction. In 1955 Lawrence further found that leukocytes dissolved in water or freeze-thaw broken, the extract still has the role of delayed transfer of allergic reactions, which can be a specific donor of cellular immune function specifically transferred to the receptor, Receptor also has the kind of cellular immunity called transfer factor (TF).