磁性微粒作为固相载体应用于生物分子的合成、分离和检测,是一种非常有效、快速和方便的方法。在挪威、英、美、德等国已实现了商业化并得到了广泛的应用,而我国目前还处于研究阶段。对磁性微粒在mRNA的分离与纯化、DNA的分离与纯化以及核酸的杂交、扩增、检测等核酸研究领域中的应用进行了较为全面的综述。 Magnetic particles as a solid support for biomolecular synthesis, separation and detection, is a very effective, fast and convenient method. In Norway, Britain, the United States, Germany and other countries have achieved commercialization and has been widely used, and our country is still in the research stage. The magnetic microparticles in the separation and purification of mRNA, DNA isolation and purification, as well as nucleic acid hybridization, amplification, detection and other nucleic acid research in the field of a more comprehensive review.