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本文探讨慢性肺心病急性发作期患者血浆血管紧张素Ⅱ(AT_Ⅱ)水平的变化及其与预后的关系。资料与方法一、研究对象按第二次全国肺心病专业会议制定的肺心病诊断标准选择慢性肺心病急性期患者37例,年龄45～80岁,男性20例,女性17例;另选择肺气肿病人13例作为对照组,年龄40～70岁,男性8例,女性5例,及健康受试者20例作为正常对照组,年龄35～71岁,男性10例,女性10例。所有病例均在入院后的第二天抽取卧位空腹时肘静脉血以作测定血浆AT_Ⅱ之用,于当天进行肺阻抗血流图检测,并观察病情变化2周。二、材料和方法 1.仪器。HB-3COG心输出仪、FJ-2008γ免疫计数仪。 2.试剂。AT_Ⅱ放免药盒由中国同位素公司北方免疫试剂研究所提供。
This article discusses the changes of plasma levels of angiotensin Ⅱ (AT Ⅱ) in acute episode of chronic pulmonary heart disease and its relationship with prognosis. Materials and methods A study of 37 patients with chronic pulmonary heart disease patients aged 45 to 80 years old, 20 males and 17 females were selected according to the diagnostic criteria for pulmonary heart disease developed by the Second National Conference of Cor Pulmonale; 13 cases of swollen patients served as the control group, aged 40-70 years, 8 males and 5 females, and 20 healthy subjects as normal control group, aged 35-71 years, 10 males and 10 females. All cases were taken on the second day after admission elbow venous blood fasting for the determination of plasma AT_ Ⅱ purposes, on the day of pulmonary impedance cardiogram detection, and observed the condition changes for 2 weeks. Second, materials and methods 1. Instruments. HB-3COG cardiac output instrument, FJ-2008γ immune counter. Reagents AT_ Ⅱ RIA kit by the China Isotope Corporation North Institute of Immunological reagents provided.