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癌基因ras蛋白在细胞的生长和分化中起重要的作用,其编码的蛋白分子量约为Mr21000,称P21蛋白,P21蛋白位于细胞浆膜内面.具有与鸟苷酸结合的能力和GTP酶的活性,参与膜的信号传递[1].癌基因ras突变,特别是第12,13和61密码子部位的点突变?
The oncogene ras protein plays an important role in the growth and differentiation of cells. The molecular weight of its encoded protein is about Mr21000, which is called P21 protein. P21 protein is located in the cytoplasmic membrane. Has the ability to bind guanylic acid and GTPase activity, involved in membrane signal transmission [1]. Oncogene ras mutations, especially point mutations at sites 12, 13 and 61 codons?