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细胞因子是免疫反应、造血和炎症反应产生和维持所必需的蛋白质类物质。如果细胞因子生成量不正常或产生部位不正常,也可以引起病理状态。细胞因子是由很多种细胞产生,也可在细胞分泌物或细胞分解物的生物产品中存在。曾有人认为血液成分中的细胞因子可介导对受者的不良反应,并可能与输血发热反应有关。使用免疫试验和生物试验,作者评估了使用包含有少白细胞策略的不同程序制备的血小板和红细胞浓缩物中
Cytokines are proteins that are necessary for immune responses, hematopoiesis, and the production and maintenance of inflammatory responses. If the cytokine production is not normal or abnormal site, can also cause pathological conditions. Cytokines are produced by a wide variety of cells and may also be present in biological products of cellular secretions or cellular breakdown. It has been suggested that cytokines in blood components may mediate adverse effects on recipients and may be related to the transfusion fever response. Using immunoassays and biological tests, the authors evaluated platelet and erythrocyte concentrates prepared using different procedures that contained a leukocyte-depleting strategy