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骨髓移植(BMT)正式应用于临床开始于70年代,现在用以治疗许多难治性血液病和小儿癌症等。日本的移植例数虽不及欧美等国,但治疗技术和效果上并无差别。一般说,根据骨髓移植的供给者不同,分为一卵双胞胎的一方为供给者的同系移植;由匹配的HLA的人作供给者的同种移植;使用患者冷冻保存的骨髓的自家移植等3种,并各有其适应症。根据上面的介绍,本文将叙述我院的治疗经验,移植方法,合并症的治疗,国内外在儿科方面BMT适应性疾病的疗效以及存在问题和展望BMT未来。
Bone marrow transplantation (BMT) officially used in clinical began in the 70s, now used to treat many refractory hematological diseases and pediatric cancer. Although the number of transplants in Japan is less than that in Europe and the United States, there is no difference in treatment technology and effect. In general, depending on the provider of the bone marrow transplant, one of the twins is divided into a homosexual transplant of the donor, a homologous transplant of a donor from a matched HLA, a home transplant of a patient’s cryopreserved bone marrow 3 Species, and each have their own indications. According to the above introduction, this article will describe the treatment experience in our hospital, transplantation methods, the treatment of comorbidities, pediatric BMT adaptive disease efficacy at home and abroad as well as the existing problems and prospects of the future of BMT.