论文部分内容阅读
保护听力是用药的一项重要原则,对儿童尤其重要。哪些药物可以引起听力损害甚至耳聋呢?抗生素:据一份调查资料披露,2500名后天聋哑人中,有850名为药物所致,占总人数的35%。引起药物性耳聋的药物形形色色,首推氨基糖甙类抗生素,大约97.2%药物性耳聋者系由庆大霉素、链霉素、卡那霉素、春雷霉素等造成的。氨基糖甙类抗生素损害耳蜗,导致毛细胞变性坏死以及螺旋器变性萎缩,引起耳聋。进一步研究发现,此类药物对听力的损害有个体差异,部分有遗传缺陷的病人即使少量用药也发生中毒,而且中毒后立即停药损害仍持续加重,医学上称为易感型中毒,具有
Protecting hearing is an important principle of medication and is especially important for children. Which drugs can cause hearing loss or even deafness? Antibiotics: According to a survey, of the 2,500 deaf and mumpy people out of 2,500, drug-induced, accounting for 35% of the total. Cause of drug deafness of all kinds of drugs, the most important aminoglycoside antibiotics, about 97.2% of drug-induced deafness by gentamicin, streptomycin, kanamycin, kasugamycin caused. Aminoglycoside antibiotics damage the cochlea, resulting in degeneration and necrosis of hair cells and spiral degeneration atrophy, causing deafness. Further study found that these drugs have individual differences in hearing impairment, some patients with genetic defects even if a small amount of medication poisoning, and poisoning immediately stop the damage continued to aggravate, medically known as susceptible poisoning, with