本文评述现代化学和免疫学领域中的一项重大发现——“催化抗体”(Catalytic Antibody,或Abzyme)及其研究进展,回顾了这一发现的分子生物学基础和背景,比较了抗体与酶之间的异同,阐述了赋予抗体催化性质的一般战略,总结了抗体-催化遵循的重要规律,预示了免疫化学的一个新分支学科——Abzymology(译名为“抗体酶学”)的崛起. This article reviews one of the major discoveries in the field of modern chemistry and immunology - “Catalytic Antibody” (Abzyme) and its research progress, reviews the foundational molecular biology background and background, The similarities and differences are described. The general strategy of conferring the catalytic properties of antibodies is summarized. The important rules followed by antibody-catalysis are summarized, which indicates the rise of Abzyzyology, a new branch of immunochemistry.