以新疆平原地区病人分离的杜氏利什曼“801”株前鞭毛期免疫BALB/c小鼠,取其脾与Sp 2/0骨髓瘤细胞融合,融合率为79％,经测定,在杂交瘤细胞内有21％对杜氏利什曼抗原起阳性反应,其中0.2％显示为特异性抗体。选特异性高的杂交瘤细胞 BALB / c mice were immunized with the pre-flagellar strain of Leuchstunds “801” isolated from patients in plain of Xinjiang Plain. The spleen was fused with Sp 2/0 myeloma cells at a fusion rate of 79%. After hybridoma 21% of cells positive for Duchenne Leishman antigen, of which 0.2% showed specific antibodies. Select specific high hybridoma cells