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目的:评价液基细胞学(TCT)检查与阴道镜下取活体组织检查(活检),并进行病理组织学检查(病检)联合应用对宫颈病变的诊断价值。方法:对2007年6月～2008年6月在该院妇科门诊就诊的1368例患者采用TCT检查。细胞学诊断采用TBS分级系统,阳性诊断包括不典型鳞状上皮(ASCUS)以上的病变,所有细胞学阳性的病人全部在阴道镜下取活检,并进行病检。结果:1368例TCT诊断阳性患者238例全部在阴道镜下取活检,并进行病检,病理组织学诊断CINⅠ73例,CINⅡ37例,CINⅢ7例SCC3例,宫颈炎118例。TCT诊断的级别越高,CIN的检出率越高。CIN的级别越高,阴道镜的检出率越高。结论:TCT联合阴道镜检查能显著提高宫颈病变的阳性检出率,对宫颈癌及癌前病变的早期诊断具有重要价值。
Objective: To evaluate the diagnostic value of combined liquid-based cytology (TCT) and colposcopic biopsy (biopsy) and histopathology (pathology) in the diagnosis of cervical lesions. Methods: From June 2007 to June 2008, 1368 patients treated in gynecology outpatient department of the hospital were examined by TCT. Cytological diagnosis using the TBS classification system, the positive diagnosis, including atypical squamous epithelium (ASCUS) lesions above, all cytology-positive patients all under biopsy colposcopy, and pathological examination. Results: Of the 1368 positive cases diagnosed by TCT, 238 cases were all under colposcopy biopsy and pathological examination, pathological diagnosis of CIN Ⅰ 73 cases, CIN Ⅱ 37 cases, CIN Ⅲ 7 cases of SCC 3 cases, 118 cases of cervicitis. The higher the level of TCT diagnosis, the higher the detection rate of CIN. The higher the CIN level, the higher the colposcopy detection rate. Conclusion: TCT combined with colposcopy can significantly improve the detection rate of cervical lesions, cervical cancer and precancerous lesions of early diagnosis is of great value.