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补骨脂素系从补骨脂中提取的有效成分。本实验采用四氮唑蓝(MTT)比色法测定补骨脂素对人白血病细胞的杀伤作用,现报告如下。资料与方法一、本院住院白血病患者4例,均为男性,年龄12～31岁。按 FAB(法-美-英)分类诊断标准,确诊为急性淋巴细胞型白血病(ALL)未缓解2例(1例外周血WBC4100/mm~3、幼稚细胞占13%,骨髓像原始+早幼淋巴细胞占91%;另1例外周血 WBC2100/mm~3、幼稚细胞占2%,异淋占7%,骨髓像中原始+早幼淋巴细胞为76.4%);急性粒细胞白血病部分分化型(M_2)2例(均系初诊:1例外周血 WBC75000/mm~3,其中幼稚细胞占75%,骨髓像原始+早幼粒细胞为80.2%;另1例外周血 WBC7000/mm~3,无幼稚细胞,
Psoralen is an active ingredient extracted from psoralen. In this experiment, tetrazolium blue (MTT) colorimetry was used to determine the killing effect of psoralen on human leukemia cells. The report is as follows. Materials and Methods 1. There were 4 patients with leukemia hospitalized in our hospital, all of whom were male and were 12 to 31 years old. According to FAB (French-American-British) classification diagnostic criteria, 2 cases were confirmed as acute lymphoblastic leukemia (ALL) without remission (1 case of WBC4100/mm~3 per week, 13% of immature cells, bone marrow as primitive + early childhood Lymphocytes accounted for 91%; the other exception was WBC2100/mm~3, 2% of immature cells, 7% of allolymph, 76.4% of primitive lymphocytes in bone marrow, and partial differentiation of acute myeloid leukemia. (M 2) 2 cases (all were newly diagnosed: one exception: WBC 75000/mm~3 of peripheral blood, 75% of which were naive cells, 80.2% of bone marrow-like primitive + promyelocytic cells; the other one was peripheral blood WBC7000/mm~3, No child cells,