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目的 探讨HBsAg阳性产妇能否进行母乳喂养。 方法 选择住院分娩的HBsAg阳性产妇 6 8例 ,收集其产后 2～ 5d母体静脉血及初乳 ,检测母血乙肝病毒标志物 (HBV M)和HBVDNA以及初乳HBVDNA。结果 母血清HBeAg阳性、HB VDNA阳性者母乳中HBVDNA检测阳性率高 ,而HBeAg阴性、HBVDNA阴性者初乳中排毒率低 ,两组比较差异有高度显著性 (P <0 .0 1)。结论 母血HBeAg、HBVDNA阳性组母乳中排毒率高 ,不宜母乳喂养。而HBeAg及HBVDNA阴性组母乳中排毒低 ,可以哺乳 ,但应给予正确的哺乳指导。
Objective To investigate if HBsAg positive mothers can breastfeed. Methods Sixty-six HBsAg positive mothers were selected for hospital delivery. The maternal venous blood and colostrum were collected 2 to 5 days postpartum. The serum HBV DNA, HBVDNA and colostrum were detected. Results The positive rate of HBVDNA in maternal serum of HBeAg positive and HBVDNA positive patients was high, while the positive rate of HBVDNA in HBeAg negative and HBVDNA negative patients was lower than that in HBVDNA negative patients (P <0.01). Conclusion The rate of detoxification in breast milk of HBeAg-positive and HBVDNA-positive mothers is high and should not be breastfeeding. The HBeAg and HBVDNA negative group of breast milk in low detoxification, you can breast-feeding, but should be given proper breast-feeding guidance.